UTHSA NMR / Screening

Overview of Services

The Biomolecular NMR Core Facility offers state-of-the-art high field NMR instrumentation for structural studies of biological macromolecules. The facility also assists in elucidating structures to support organic synthesis projects, and in NMR-based drug discovery. The resources of the facility can be accessed either on a fee-for-service or on a collaborative use basis. The NMR instruments are accessible to trained users 24 hours per day, year-round.

Services:

• Training to operate NMR spectrometers and software
• Peptide assignment and structural integrity
• 3D structure determination of biological macromolecules
• Mapping binding interfaces
• Fragment-based screening
• Metabolomics (coming soon)

Instrumentation:

• Bruker AvanceIII 500 MHz spectrometer equipped with a 1.7 mm-cryoprobe and SampleJet
• Bruker Avance 600 MHz spectrometer equipped with a 5 mm-cryoprobe
• Bruker Avance 700 MHz spectrometer equipped with a 5 mm-cryoprobe and SampleXpress
• Jasco 815 Circular Dichroism Spectrometer

Leadership

Dmitri N. Ivanov, Ph.D., Director
Phone: (210) 567-8781 
Email: ivanov@uthscsa.edu

Kristin E. Cano, Ph.D., Technical Director
Phone: (210) 567-8706
Email: CanoK@uthscsa.edu

Location and hours of operation

Links and Resources

1. Biomolecular NMR Spectroscopy Webpage

Contacts

Map