UTHSA NMR / Screening

Overview of Services

The Biomolecular NMR Core Facility offers state-of-the-art high field NMR instrumentation for structural studies of biological macromolecules. The facility also assists in elucidating structures to support organic synthesis projects, and in NMR-based drug discovery. The resources of the facility can be accessed either on a fee-for-service or on a collaborative use basis. The NMR instruments are accessible to trained users 24 hours per day, year-round.

 

 

Services:

  • Training to operate NMR spectrometers and software
  • Peptide assignment and structural integrity
  • 3D structure determination of biological macromolecules
  • Mapping binding interfaces
  • Fragment-based screening
  • Metabolomics (coming soon)

 

Instrumentation:

  • Bruker AvanceIII 500 MHz spectrometer equipped with a 1.7 mm-cryoprobe and SampleJet
  • Bruker Avance 600 MHz spectrometer equipped with a 5 mm-cryoprobe
  • Bruker Avance 700 MHz spectrometer equipped with a 5 mm-cryoprobe and SampleXpress
  • Jasco 815 Circular Dichroism Spectrometer

 

Leadership

 

Dmitri N. Ivanov, Ph.D., Director
Phone: (210) 567-8781 
Email: ivanov@uthscsa.edu

 

Kristin E. Cano, Ph.D., Technical Director
Phone: (210) 567-8706
Email: CanoK@uthscsa.edu

 

 

 

Location and hours of operation

Hours Location

Monday - Friday 9:00am-6:00pm 

8403 Floyd Curl Drive
UTHSCSA Greehey Campus
Research Administration Building
San Antonio, TX 78229

 

Links and Resources

  1. Biomolecular NMR Spectroscopy Webpage

Contacts

Name Role Phone Email Location
Kristin E. Cano, Ph.D.
Technical Director
 
210-567-8706
 
canok@uthscsa.edu
 
RAB 5.210
 
Dmitri N. Ivanov, Ph.D.
Director
 
210-567-8781
 
ivanov@uthscsa.edu
 

 

Service list


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Fragment Based Screening (HSQC) (1)

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