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Biospecimen and Translational Genomics Core

Overview of Services

The Biospecimen and Translational Genomics Core Laboratory offers services in the following four categories:  

 

BioBanking

  • Services for biological sample processing and storage
  • Assistance with submission of regulatory documents for human studies
  • Histology services
  • Isolation of nucleic acids from biological specimens
  • Quantity and quality assessment of nucleic acids (Nanodrop spectrophotometer and Agilent Bioanalyzer)
  • Epstein-Barr Virus transformation of lymphocytes to establish lymphoblastoid cell lines 

Genotyping

  • High throughput genotyping of single nucleotide polymorphisms (SNPs) using Agena Mass Array technology
  • TaqMan allelic discrimination analysis using a Bio-Rad CFX96 and CFX384 Touch real-time PCR system
  • Absolute quantification of DNA copy number with a Bio-Rad QX200 droplet digital PCR system

Gene Expression

  •  Whole genome gene expression microarray analysis for human and model organisms (Agilent GE microarrays in various formats)
  •  Targeted gene expression analysis using the TaqMan real-time quantitative PCR or SYBR Green methods and the Bi-Rad CFX96 and CFX384 Touch real-time PCR systems
  •  Absolute quantification of RNA transcripts with a Bio-Rad QX200 droplet digital PCR system
  •  Access to Agilent GeneSpring analysis software

Digital Slide Scanning

  •  Brightfield and fluorescent imaging of tissues with an Aperio VERSA

 

Leadership

 

Robin J. Leach, Ph.D., Director

Email: leach@uthscsa.edu

Phone: 210.567.6947

 

Teresa L. Johnson-Pais, Ph.D., Co-Director

Email: paist@uthscsa.edu

Phone: 210.567.6571

 

Location and hours of operation

Hours Location

Monday - Friday

8 AM - 5 PM

*Self Use equipment is available 24/7 for trained users                

 

University of TX Health Science Center    

7703 Floyd Curl Drive - Long Campus

Real Time Instruments 5.570C MED

8403 Floyd Curl Drive - North Campus RAB

Biospecimen Lab/Freezers/Aperio Versa 200

1.108.6 RAB 

San Antonio, TX 78229

 

 

 

Contacts

Name Role Phone Email Location
Teresa L. Johnson-Pais, Ph.D.
Co-Director
 
210.567.6571
 
paist@uthscsa.edu
 
5.542E MED
 
Robin Leach, Ph.D.
Director
 
210.567.6947
 
leach@uthscsa.edu
 
5.552C MED
 

Services & Rates


Search available services: View: by category alphabetically
Biobanking (17)
Genotyping Services (5)
Gene Expression (11)
Equipment Usage (2)
Labor (4)